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Mild or moderate (Little one Pugh Course A or B): The dose must not exceed ten mg as soon as a day. The use ofCIALIS once every day has not been extensively evaluated in individuals with hepatic impairment and so, caution is advised.
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CIALIS is usually a substrate of and predominantly metabolized by CYP3A4. Reports have revealed that medicines that inhibit CYP3A4 can maximize tadalafil exposure.